xCONTENTS1 Background and History, 12 Basic Cell Biology: Structure and Function of Genesand Chromosomes, 63 Genetic Variation: Its Origin and Detection, 284 Autosomal Dominant and Recessive Inheritance, 605 Sex-Linked and Nontraditional Modes ofInheritance, 796 Clinical Cytogenetics: The Chromosomal Basis ofHuman Disease, 1037 Biochemical Genetics: Disorders of Metabolism, 1328 Disease-Gene Identification, 1549 Immunogenetics, 18010 Genetic Basis of Development, 19711 Cancer Genetics, 21712 ...